5-CL-ADB-A, also known as MDMB-4en-PINACA and MDMB-PENINACA, is an indazole-based synthetic cannabinoid in the indazole-3-carboxamide family. Its official scientific nomenclature is methyl (S)-3,3-dimethyl-2-(1-(pent-4-en-1-yl)-1H-indazole-3-carboxamido)butanoate (C20H27N3O3) .
Scientific Studies MDMB-4en-PINACA
No official scientific studies have been done on 5CL-ADB-A to date. However, in 2018 a study published in “Forensic Toxicology” compared the potency and mechanisms of several carboxamide-type synthetic cannabinoids. These compounds, like 5CL-ADB-A, have asymmetric carbon, derived from an amide moiety composed of amino acid derivatives.
5-cl-adb-a behave in similar ways since they are analogues with similar structures. Indeed, the study found that all such synthetic cannabinoids are agonists that act on both CB1 and CB2 cannabinoid receptors in the body’s endocannabinoid system. This suggests they have a cannabimimetic effect. Thus, can be potentially more potent than cannabis’s psychoactive compound THC. THC works by acting on these same cannabinoid receptors.
The study looked at AB-FUBINACA, EMB-FUBINACA, 5F-EMB-PINACA, APP-CHMINACA and MDMB-FUBICA. They all have similar structures to 5CL-ADB-A. This chemical acts on CB1 and CB2 receptors thus it would present similar cannabimimetic effects.