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a-pihp powder

alpha-Pyrrolidinohexiophenone (also known as α-PiHP, a-PHiP, and 4-methyl-alpha-pyrrolidinopentanophenone) is a lesser-known novel stimulant substance of the cathinone and pyrrolidinophenone classes. It is structurally related to MDPV and A-PHP and is one of the latest successors to the designer drug cathinone analog A-PVP.

Users taking this substance note subjective effects of euphoria, thought acceleration, disinhibition and ego inflation. Generally, it comes in the form of either a fine powder or crystallized shards. It produces powerful but short-lived euphoric stimulant effects. Users report it to be more compulsive in nature (and strength) to vaporized methamphetamine. Like its cathinone predecessors, it is has gained notoriety for its tendency to induce compulsive redosing and addictive behaviors as well the ability to produce delusional states and psychosis when abused. The compulsivity induced in A-PiHP seems to be stronger compared to similar substances in this class, as reported by online anecdotal reports.

Very little data exists about the pharmacological properties, metabolism, and toxicity of α-PiHP. It has recently become commonly marketed as a legal, grey-market alternative to a-PHP, 3-MMC, and A-PVP. Also,  research chemical vendors commercially distribute it online.

It is highly advised to use harm reduction practices if using this substance.


The mechanism of action of α-PiHP is unknown. Users believe it acts similarly to the designer drug pentedrone and α-PVP in addition to its substantially shorter duration. Both act as a potent norepinephrine-dopamine reuptake inhibitors(NDRI) without being neurotransmitter releaser. However, researchers have not yet conducted any substantial research on the pharmacology of this compound.

This means it may effectively boost the levels of the norepinephrine and dopamine neurotransmitters in the brain by binding to and partially blocking the transporter proteins that normally remove those monoamines from the synaptic cleft. This allows dopamine and norepinephrine to accumulate within the brain, resulting in stimulating and euphoric effects.

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5g, 10g


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