Description

O-DSMT Powder

O-Desmethyltramadol (also known as O-DSMT and desmetramadol) is an opioid substance of the phenylpropylamineclass. It is an active metabolite of tramadol.

O-DSMT has no documented history of human use before it appeared for sale on the research chemical market in the 2010s.

Subjective effects include sedation, pain relief, anxiety suppression, muscle relaxation, and euphoria. However, scientists compare O-DSMT to be less stimulating and feels considerably close to a traditional opiate like tramadol. Being the metabolite that is mainly responsible for the analgesic effect of tramadol, O-DSMT is significantly more potent by weight than its parent compound.

Humans don’t use O-DSMT frequently because of its unavailability. Thus, can not talk much about its toxicity and abuse potential. Medics highly advise to use harm reduction practices if using this substance.

Physical effects of O-DSMT

• Users describe the general sensation of O-DSMT to be of intense euphoria, relaxation, anxiety suppression and pain relief.
  • Pain relief
  • Physical euphoria –
  • This particular substance can be considered as less intense in its physical euphoria when compared with that of morphine or diacetylmorphine (heroin).
  •  The sensation gives extreme feelings of intense physical comfort, warmth, love and bliss.
  • Itchiness
  • Respiratory depression – At low to moderate doses, this effect results in the sensation that the breath is slowed down mildly to moderately, but does not cause noticeable impairment. At high doses and overdoses, opioid-induced respiratory depression can result in a shortness of breath, abnormal breathing patterns, semi-consciousness, or unconsciousness. Severe overdoses can result in a coma or death without immediate medical attention.
  • Constipation
  • Cough suppression
  • Difficulty urinating
  • Nausea
  • Sedation
  • Pupil constriction
  • Decreased libido
  • Appetite suppression
  • Orgasm suppression

Toxicity and harm potential

O-DSMT has a moderate potential toxicity relative to its dose due to its potency. As with all opioids, long-term effects can vary but can include diminished libido, apathy and memory loss. It is also potentially lethal when mixed with depressants like alcohol or benzodiazepines.

Vendors market O-DSMT as a currently legal substitute for illegal opioid drugs, either in powder form or mixed into various other preparations. They sell one such blend under the brand Krypton which contains powdered kratom leaf (Mitragyna speciosa) laced with O-DSMT